ARGEN

ARGEN for Aggregation and Stability Analysis

Smarter Product Development
Early Detection of Aggregation
Understand Impact of Thermal, Chemical and Mechanical Stress
Rank the Stability of Proteins, Peptides and other Products

ARGEN, by Fluence Analytics, adds another powerful tool to the arsenal of biopharmaceutical and polymer scientists. This static light scattering instrument measures the pharmaceutical stability of therapeutic proteins and peptides and the quality of natural and synthetic polymers. The instrument is composed of 16 independent cuvette sample cells capable of precise control of thermal, chemical and mechanical stress. By continuously monitoring the state of its samples, the lab instrument provides continuous, kinetic data yielding early detection of aggregation, degradation and particle formation under independently controlled stressor conditions.

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ARGEN Features

Realtime Monitoring

Determine each sample’s molar mass evolution, aggregate formation and phase stability in real time

Continuous Operation

Exchange individual samples without affecting other ongoing experiments

Application of Stress

Apply combinations of thermal, chemical and mechanical stress to each sample

Intuitive Software

– View experiments in real time

– Adjust individual stressors before or during experiments

 KEY OUTPUTS
  • Aggregation Rate
  • Mass Aggregation Rate
  • Normalized Mw